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PEN vs PTGX

Penumbra, Inc. vs Protagonist Therapeutics, Inc. — AI-powered side-by-side comparison
PEN
Penumbra, Inc.
67
Buy
VS
PTGX
Protagonist Therapeutics, Inc.
65
Buy
MetricPENPTGX
AI Score 67 65
Price $326.07 $148.25
P/E Ratio 79.78× 121.74×
ROE 12.4% -21.2%
Revenue Growth YoY
Gross Margin 67.8% 99.9%
Debt / Equity 0.14× 0.01×
Dividend Yield 0.0% 0.0%
RSI (14) 79.6 68.1
Beta 0.701 1.794
Expected Upside +6.3%

AI Committee View

Current Innellis committee reasoning for PEN versus PTGX.
PEN leads by 2 points.

PEN scores 67/100 (Buy) versus PTGX at 65/100 (Buy).

PEN Committee View
80% agreement
5 analysts

The primary driver is vix regime is low -- calm backdrop supports risk-taking. The main limiting factor is 2 consecutive earnings misses -- execution concerns. The committee is constructive but not yet at full conviction.

Bull Case
  • Quarter-over-quarter growth rate is ACCELERATING, not just positive — Growth
  • Price structure making higher highs and higher lows — Technical
  • MACD histogram positive -- bullish momentum — Technical
Bear Case
  • 2 consecutive earnings misses -- execution concerns — Growth
  • RSI at 80 is in overbought territory — Technical
PTGX Committee View
67% agreement
6 analysts

The committee is genuinely divided. Growth Analyst sees a compelling case — revenue growing 34.8% yoy -- genuine top-line momentum. Value Analyst remains cautious — p/e of 115.4 is expensive by classic value standards. This disagreement is itself the signal — the setup is not clean in either direction.

Bull Case
  • Revenue growing 34.8% YoY -- genuine top-line momentum — Growth
  • EPS growing 46.0% YoY — Growth
  • Price structure making higher highs and higher lows — Technical
Bear Case
  • P/E of 115.4 is expensive by classic value standards — Value
  • Price-to-book of 8.9x prices in significant intangible value — Value
  • Weekly RSI at 84 -- overbought on the larger timeframe too — Technical
Want the full breakdown?
Committee votes, technicals, and trade plans for both companies.
PEN Full Analysis PTGX Full Analysis