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PSNL · NASDAQ · STOCK

Personalis (PSNL) Stock Analysis

Healthcare Updated October 10, 2026
$15.99
52W $4.96 – $18.89
56/100
$1.71B
-14.7
2.32
AI Committee Verdict
Buy
56/100
Conviction: Contested · 50% agreement · 6 analysts
+2.3%
-27.9%
0.08:1
Contested
⚠
Buy rating, but near-term risk/reward is unfavorable
The long-term recommendation is based on the composite investment score. The near-term risk/reward is based on nearby support and resistance levels. These can differ when a strong company trades close to resistance with support further below.

Is PSNL Bullish or Bearish?

Bullish. Innellis AI committee rates Personalis, Inc. (PSNL) Buy with a composite score of 56/100 , based on 6 analysts with 50% agreement. Last updated October 10, 2026.

What Would Change This View

Upgrade to Strong Buy
Requires a committee score of 75.0 — +18.75 from today. Applies on the first day at or above the line; upgrades are never dampened.
Downgrade to Watch
Requires the score to fall below 55.0 — -1.25 from today. The band boundary is 60.0, but a one-step downgrade must clear a further margin first. A score oscillating around the line should not change the rating every night.

Executive Summary

The committee is genuinely divided. Risk Analyst sees a compelling case — low leverage (debt-to-equity 0.02) -- balance sheet can absorb a shock. Portfolio Manager remains cautious — sector concentration is already high (hhi 2796.97). This disagreement is itself the signal — the setup is not clean in either direction.

Bull & Bear Case

Bull Case
  • Quarter-over-quarter growth rate is ACCELERATING, not just positive — Growth
  • Low leverage (debt-to-equity 0.02) -- balance sheet can absorb a shock — Risk
Bear Case
  • ROE of only -46.5% -- cheap may mean cheap for a reason — Value
  • Revenue declining -13.3% YoY -- this is not a growth story right now — Growth
  • 2 consecutive earnings misses -- execution concerns — Growth
  • MACD histogram negative -- bearish momentum — Technical
Both cases are generated from quantitative data signals, not qualitative or forward-looking judgement. They summarise what the numbers say today.
Price History (6M)

AI Investment Committee

Committee Consensus As of October 10, 2026
Overall Committee Score
56/100
Agreement
50%
Analysts
6
Conviction
Contested
Sector Rank
Top 58%
of 192 Healthcare peers
Value Analyst neutral
52 / 100 · Moderate confidence
Fair value -- neither a bargain nor obviously overpriced
− ROE of only -46.5% -- cheap may mean cheap for a reason
Growth Analyst bearish
40 / 100 · High confidence
Growth story is weak, decelerating, or inconsistent
+ Quarter-over-quarter growth rate is ACCELERATING, not just positive
− Revenue declining -13.3% YoY -- this is not a growth story right now
Technical Analyst neutral
48 / 100 · High confidence
Mixed or range-bound price action
− MACD histogram negative -- bearish momentum
Risk Analyst bullish
75 / 100 · Moderate confidence
Risk profile is manageable -- leverage, volatility, and event exposure all look contained
+ Low leverage (debt-to-equity 0.02) -- balance sheet can absorb a shock
Macro Analyst bullish
65 / 100 · Low confidence
Macro backdrop is supportive of risk assets generally, and this name's beta works in its favor
News Analyst neutral
58 / 100 · Low confidence
News flow is mixed or quiet -- no strong signal either way right now
Portfolio Manager bearish
30 / 100 · Moderate confidence
The existing book itself argues for caution here, independent of how good this specific stock looks
− Sector concentration is already high (HHI 2796.97)
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Investment Thesis Evolution

Committee score moved marginally from 56.2 to 56.2.

Comparing 2026-10-09 to 2026-10-10 (1 day apart).

Technical Analysis

RSI (14)
37.3
Neutral
MACD Histogram
-0.096
Bearish Momentum
Trend Direction
Sideways
Weekly: Uptrend
Market Structure
Mixed
Support
$11.54
Resistance
$16.36
Bollinger %B
0.10
Inside Bands
Price vs Moving Averages
EMA 9
$16.15 Below
EMA 21
$16.20 Below
EMA 50
$15.53 Above
EMA 200
$11.75 Above

Fundamental Analysis

Valuation
71
Growth
58
Profitability
0
Financial Health
100
Cash Flow
15
Valuation
P/E Ratio -14.7×
P/B Ratio 7.17×
PEG Ratio -3.86
Dividend Yield 0.00%
52W High $18.89
52W Low $4.96
Quality & Growth
ROE -3111.6%
ROA -2432.0%
Gross Margin 1268.6%
Operating Margin -16407.4%
Revenue Growth YoY —
Debt / Equity 0.16
AI Fundamental Assessment
P/E ratio of -14.7 (inexpensive relative to a 15-40x range); Price-to-book of 7.2x; PEG ratio of -3.9 (under 1.0 suggests growth is undervalued relative to price); Return on equity of -31.1%; Return on assets of -24.3%; Net margin of -153.8%; Gross margin of 12.7%; Current ratio of 5.28 (healthy short-term liquidity); Debt-to-equity of 0.16; Free cash flow per share is negative (-0.96); Most recent quarter missed estimates by 13.2%; 2 consecutive earnings misses; EPS growth accelerating (-11.5% -> -3.4% QoQ); Analyst estimates rising over recent quarters
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